It was divided during the English Civil War, bombed in the First World War and, miraculously, survived the mass devastation inflicted on the city during the Blitz.
Now, another chapter has been added to Holy Trinity Church.
This week, church and business leaders gathered for the unveiling of a new brand, logo and website designed to promote England's largest parish church as "an amazing place", with its extraordinary heritage, architecture and spiritual depth.
The Reverend Canon Dr Neal Barnes, the vicar of Holy Trinity, says he is keen for the public to see how the church is now being used in many surprising and exciting ways.
He said: "For the first time we have a brand, visual identity and website that, while respecting the past, reflect the reality of Holy Trinity today. This is a truly amazing place where people share amazing experiences.
"Holy Trinity is, of course, primarily a wonderful place of worship in a magnificent setting, rich in heritage.
"But it is also a surprising, vibrant and creative place, used by so many different people and community groups and playing an important part in the life of our great city."
Dr Barnes says Holy Trinity will be at the forefront of regeneration plans.
"We have very exciting plans to make a major contribution to the regeneration of Hull as a centrepiece of the Old Town and we now have a high-quality brand and online presence that support those ambitions," he said.
Holy Trinity worked with award-winning brand specialists H&H, based in Hessle, to develop the new identity, which uses the H and T initials to echo the church's profile against the Hull skyline, and a clean and contemporary website, with a new web address – holytrinityhull.com
H&H Director Hannah Thoresby said: "The creation of Holy Trinity's new brand involved much more than a simple redesign of its logo.
"Working with Neal's team we helped them to define their entire personality – from the way they communicate, behave and present themselves, to the way they get across everything that Holy Trinity offers to the people of Hull and beyond.
"We built the brand from the inside out – capturing the essence of Holy Trinity from its people, looking at who they are now, who they want to be and how they want people to perceive them. In this way we were able to articulate the brand in a way that truly reflects what Holy Trinity is now and its future ambitions.
"The new website is an important part of the brand launch, giving people a chance to connect with Holy Trinity in ways that they might not have considered possible in the past."
Holy Trinity was founded by Edward I in the late 13th century around the time he granted the former settlement of Wyke a Royal Charter and renamed it Kings Town upon Hull.
The church is, therefore, as old as the city of Hull itself and a repository of so much of the city's history.
Hull's greatest son, the abolitionist MP William Wilberforce, was baptised in the font that is still used regularly for Christenings.
The 17th-century poet Andrew Marvell worshipped at Holy Trinity and the church is proud to be home to tributes to the city's war dead and some of the many thousands from Hull lost at sea.
In recent years, Holy Trinity has undergone something of a renaissance to become a vibrant, progressive presence in the city centre and a beacon for the revival of Hull's Old Town.
Services have been swelled by newcomers.
Holy Trinity is reaching out to the community in many new and unexpected ways.
It has found new uses as a location for fashion shows, art installations, concerts and even beer festivals.
Kathryn Shillito is city centre manager of Hull Business Improvement District (Bid), one of the community partners supporting the church's move into dot-com territory.
She said: "Hull Bid acknowledges the important and integral role Holy Trinity Church plays within Hull city centre.
"In recent years, we have witnessed the church really embedding itself into the community by hosting a range of activities and unique events, including our own Hull Fashion Week, the Hull Trinity Music Festival and the popular Camra beer festival.
