Health officials are urging people across East Yorkshire to be aware of the symptoms of meningitis and meningococcal septicaemia.
Meningitis, which is inflammation of the brain, and meningococcal septicaemia – or blood poisoning – can be caused by the bacterium meningococcus. Anyone can be affected by the diseases.
But most cases are recorded in children under the age of five. Teenagers and young adults are also vulnerable and cases are often recorded among university and college students.
Meningococcal disease does not spread easily from person to person, so health experts said the majority of cases occur "sporadically".
Dr Stephen Morton, regional director for the Health Protection Agency in the Yorkshire and Humber region, said: "Meningococcal disease is a serious illness which is more prevalent in the winter months.
"In 2011, there were around 150 cases of meningococcal infection in Yorkshire and the Humber.
"The illness progresses rapidly, so it is extremely important to remain aware of the symptoms and to seek urgent medical help if there is any concern at all."
Symptoms can include a high temperature, vomiting, severe headache, stiff neck, aching limbs and joints, a dislike of bright lights, drowsiness or a rash which does not fade when pressed.
In small babies, a refusal to feed and a high pitched cry may also be symptoms.
Further advice, as well as information about meningitis and vaccinations, is available by visiting www.nhsdirect.nhs.uk, or calling NHS Direct on 0845 4647.
The National Meningitis Trust can be contacted on 0800 0281828, or call the Meningitis Research Foundation on 080 88003344.
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Watch out for signs of meningitis
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